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Prohibition is best defined as:

  1. Permission

  2. Restriction

  3. Ban

  4. Acceptance

The correct answer is: Ban

Prohibition is best defined as a "ban," which implies a formal or legal order that forbids specific actions or practices. This term often denotes a strict and enforced policy that disallows certain behaviors or substances, such as the historical context of banning alcohol in the United States during the Prohibition era. The concept of prohibition conveys a clear and unequivocal restriction on activities deemed undesirable or harmful to society. In contrast, terms like permission and acceptance indicate approval or allowance, which stand in opposition to the idea of prohibition. Restriction may seem similar but does not carry the same connotation of total forbiddance; it can imply limitations rather than an outright ban. Thus, recognizing prohibition as a ban captures the essence of the term with its strong enforcement aspect, reflecting the nature of rules that aim to eliminate specific actions completely.