Kaplan Nursing Entrance Practice Exam

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Individuals with the homozygous bb genotype typically have what characteristic?

Brown eyes
Blue eyes
Green eyes
Hazel eyes

The correct answer is: Blue eyes

Individuals with the homozygous bb genotype typically have blue eyes due to the inheritance of eye color traits. Eye color is primarily determined by multiple genes, but one of the key genes is the OCA2 gene, which influences melanin production in the iris. The presence of two recessive alleles, represented as 'bb,' means that there is a lower level of melanin in the iris, resulting in blue rather than brown or green eyes. In contrast, the homozygous BB genotype would typically lead to brown eyes, as this gene variant promotes higher melanin levels. Other colors, such as green and hazel eyes, can result from variations in alleles and their interactions but are not specifically associated with the homozygous bb genotype. Therefore, blue eyes are characteristic of individuals with that specific genotype.