Kaplan Nursing Entrance Practice Exam

An individual with one X chromosome is phenotypically which gender?

1. Male

2. Female

3. Intersex

4. Unknown

The correct answer is: Female

An individual with one X chromosome would typically be phenotypically classified as female. In humans, biological sex is generally determined by the presence of sex chromosomes. Typically, females have two X chromosomes (XX), while males have one X and one Y chromosome (XY). There are specific genetic anomalies that can result in variations (such as Turner syndrome, where an individual has a single X chromosome and is phenotypically female), but in general terms, the absence of a Y chromosome suggests a female phenotype. The options representing male, intersex, or unknown do not align with the chromosomal configuration outlined in the question. An individual with only one X chromosome lacks the Y chromosome necessary to categorize as male, and while intersex conditions exist, they are not implied by simply having one X chromosome without additional information about other chromosomes. Thus, the most accurate classification based on standard chromosomal patterns is female.